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Values are the ratio of GST activity in tumor tissue with GST activity in normal tissue

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(1996, Journal of Endocrinology) reported IGF-1 LR3 was 1.5-2x more potent than equimolar native IGF-1 for body weight gain, organ growth, and anti-catabolic effects when continuously infused in normal and dexamethasone-treated rats

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Natural compounds often have low aqueous solubility or are rapidly metabolized, leading to minimal absorption in vivo

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10.3389/fphar.2019.00382 [DOI] [PMC free article] [PubMed] [Google Scholar] 236.Dai G, Vaughn S, Zhang Y, Wang ET, Garcia-Cardena G, Gimbrone MA

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Interestingly, a paleolithic diet seemed to have positive effect on clinical improvement, as it is a natural source of nutrients similar to supplements, improving the function of thyroid gland in HT and Graves disease natural history [120]

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