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However, many of them have serious concerns about the long-term use of these drugs

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Moreover, subsequent research should investigate the prospective contributions of these interventions beyond sarcopenia, particularly in the realms of preventing or alleviating age-related vascular aging, metabolic syndrome, and frailty

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In mammals, the mtDNA encodes only 37 genes, of which 13 are subunits of the OXPHOS (complexes I, III, IV, and V), two are rRNA genes, and 22 are tRNA genes required for mitochondrial protein synthesis

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Research published in the New England Journal of Medicine demonstrated that restoring growth hormone levels in older adults produced measurable improvements in body composition, including increased lean mass and decreased fat mass (2)

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