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GPX4 catalyzes the reduction of hydrogen peroxide and lipid hydroperoxides at the expense of GSH

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Molecular studies presented in the book focus on the regulation of these enzymes and identify important response elements

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For example, the silent information regulator 1 (SIRT1), a NAD + -dependent protein deacetylase, functions as a key upstream regulator for LKB1/AMPK signaling in the liver 50