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Finally, by increasing the affinity of lipoprotein (a) for fibrin, homocysteine would inhibit the conversion of plasminogen into plasmin on the fibrin surface (Harpel et al, 1992

460 Patients with T2DM complicated with the multivessel disease have a significantly higher risk of ischemic events and overall mortality than those with T2DM with single-vessel disease

These effects were achieved through the regulation of the Akt/mTOR/GSK-3 signaling pathway, positioning ESP as a promising therapeutic agent for addressing cognitive decline associated with AD (Luo et al., 2022)

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