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When to seek medical care: Contact your healthcare provider promptly if you experience severe or persistent abdominal pain, pain that radiates to your back, persistent vomiting, inability to pass gas or stool, yellowing of skin/eyes, fever with abdominal symptoms, or signs of dehydration

Neuropharmacological and Pharmacokinetic Properties of Berberine: a Review of Recent Research

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doi: 10.1016/j.cmet.2021.07.007 44 ZhangXZhangYWangPZhangSYDongYZengGet al

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For instance, some patients may eat later in the evening to minimise daytime nausea, potentially affecting sleep onset or quality