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This effect is associated with increased insulin signal transduction via phosphatidylinositol-3-OH kinase in the liver (but not in the skeletal muscle) and with reduced hepatic expression of the gluconeogenic genes, glucose-6-phosphatase and phosphoenolpyruvate kinase (German et al., 2009)

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Fusion Polypeptides of Human Serum Albumin and a Therapeutically Active Polypeptide (Google Patents, 2004)

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Local players have launched these drugs under their own local brands and many are gearing up to manufacture for sale to markets with no patents, as well as lying in wait for large-scale generic manufacturing for the local market as well once the India semaglutide patent expires in March 2026

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