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Amino Acid Sequence and Structural Modifications Semaglutide consists of 31 amino acids , with substitutions and conjugations enhancing stability: Amino Acid Sequence (N C terminus): rCopyEdit HisAibGluGlyThrPheThrSerAspValSerSerTyrLeuGluGlyGlnAlaAlaLysGluPheIleAlaTrpLeuValArgGlyArgGlyOH Key Structural Features: Aib (-aminoisobutyric acid) at position 2 replaces Ala to enhance resistance to DPP-4 degradation

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