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Step 3: GHK-Cu and PDRN topical application through open microchannels Immediately following the microneedling session, GHK-Cu serum is applied to the treatment area while the microchannels are fully open

Available information derives from animal studies or from mechanistic reasoning

Tumor cells, indeed, have shown higher levels of GSH than normal cells and often are characterized by an overexpression of GSH-related enzymes and proteins that lead to a better resistance to antineoplastic treatments and, possibly, could favor chemoresistance [116,117,118]

ChEIs function by preventing ACh degradation within synaptic gaps, thereby enhancing neuronal communication and cognitive function

GHK-Cu is a small peptide made of three amino acids (glycine, histidine, lysine) bound to a copper ion

The biochemistry of sirtuins