Real-world data plays a critical role in helping to evaluate how therapies perform across broader, more diverse populations in everyday care
Prevention or delay of type 2 diabetes and associated comorbidities: standards of care in diabetes-2023
Regarding NAFLD, empagliflozin, in particular, has shown positive effects regarding liver fat content, as measured by Magnetic Resonance Imaging-Proton Density Fat Fraction (MRI-PDFF) and Control Attenuation Parameter (CAP), 60,61 and liver fibrosis, as measured by liver stiffness determination 63 and various indexes, such as the FIB4 index and NAFLD fibrosis score
Limited data from unintentional exposures to GLP1-RAs in early pregnancy (at least 500 pregnancies) suggest no increased risk of birth defects compared to pregnancies in women with similar conditions
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Injecting early during the pre-steady-state phase is riskier than injecting early at steady state