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Activation of the CaSR, when there are normal levels of serum calcium, results in increased proteolysis of PTH resulting in little secretion of the hormone from the parathyroid gland

Interrogation of specific cell-cell interactions using new tools such as bar-coded viral tracing technology, is beginning to identify specific molecular interactions, for example that Sema4d and EphrinB3 expressed by microglia control astrocyte responses respectively through PlexinB2 and EphB3 receptors

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