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Acta Clinica Belgica

In rodents, modafinil, a wake-promoting drug that mediates dopamine-related psychostimulant action, prevented LPS-induced anxiety-like and depressive-like behaviors, as well as the LPS-induced increase in CD11b + CD45 high cells and IL-1 gene expression in the brain (Zager et al., 2018)

The resulting cDNA underwent end-repair, A-tailing, and ligation to NEBNext adapters

Confirmed at 28 days A follow-up 28-day study (Babula et al., 2024) extended the finding: 5-Amino-1MQ dose-dependently limited body weight and fat mass gain without changing food intake, and it improved liver markers in obese mice

Glazer, K