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400,401,402 In liver diseases like non-alcoholic fatty liver disease (NAFLD) and cirrhosis, mitochondrial dysfunction leads to impaired fatty acid oxidation, excessive ROS production, and oxidative stress

To accomplish sustainable weight loss, its essential to focus on long-term lifestyle habits to help maintain weight loss after stopping the medication

Wettergren A, Wojdemann M, Meisner S, Stadil F, Holst JJ

Moreover, previous studies have indicated that oxyntomodulin, which binds to both the glucagon receptor and the GLP-1 receptor, increases energy expenditure and decreases energy intake [75]

About this article Cite this article Sahiner, U.M., Birben, E., Erzurum, S

Therefore, it cannot be excluded that the modest reduction in body weight contributed in part to the improvement in insulin sensitivity in all groups