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It is possible that combination therapy offers advantages over monotherapy, opening the debate on whether it should always be adopted as first-line treatment, reserved only for a brief initial phase followed by maintenance monotherapy, or applied only in patients who do not respond to monotherapy

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Managing Side Effects and Staying Comfortable Nausea is the most common side effect, affecting roughly thirty percent of users in the first month

If discontinuation is necessary due to side effects or other concerns, this decision should be made in consultation with the prescribing healthcare provider