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In the same trial, 44% of participants on 9 mg mazdutide reached at least 20% weight loss, versus 2.6% on placebo

For patients with severe hyperglycemia at diagnosis, tirzepatide monotherapy can achieve glycemic targets that might otherwise require combination therapy

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Funding extensions will be submitted to the executive sponsors for approval on a case-by-case basis

Journal reference: Abou-Khalil R., Andary J., and El-Hayek E

Studies have also explored its use for fatigue and cognitive symptoms, though results have been mixed (Gaede et al., 2017