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(2) Some case reports describe success with dexmedetomidine in cases which were refractory to other sedatives (including benzodiazepines).(23117910, 25169248) (3) Dexmedetomidine doesnt suppress respiration, so it is less likely to precipitate intubation
It also shows activity at MC3R and MC4R receptors involved in appetite and sexual function pathways
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