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82 Five out of the seven studies showed some positive results, but there was significant heterogeneity between individual study results that was not explained by NAC dose, duration of treatment or severity of depressive symptoms at baseline

One of the key components of aloe is barbaloin which is metabolized to aloe-emodine-9-anthrone by intestinal bacteria

doi: 10.1016/j.envint.2025.109391 11 SunSShenJJiangJWangFMinJ

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Niacin (Vitamin B-3)

Feb 8 2020;21(3)doi:10.3390/ijms21031135