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LAR is a TNBC subtype sensitive to CD36-induced ferroptosis We finally evaluated the expression of CD36 in a large cohort of patient-derived xenograft (PDX) derived from breast cancer patients classified in six different triple negative subgroups according to Lehmann classification [27] (Fig

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This phenomenon relates to the rapid change in glucose levels rather than a direct medication toxicity

GST plays roles in signal transduction pathways via interaction with signaling kinases such as JNK and Cdk2

Normally, only 10-15% of scalp hairs remain in this resting phase, but metabolic stress can push up to 30% of follicles into telogen simultaneously

94,265,266,267 Moreover, in vascular cells, upregulation of growth factors like PDGF has been noted, which can promote smooth muscle cell proliferation and atherosclerosis