VARIOUS TRIALS WITH GSH AND OTHER ANTIOXIDANTS There are various clinical trials involving GSH to investigate GSH transportation across the intestinal epithelium [35], therapeutic effects of oral adminis- tration of glutathione in patients with non-alcoholic fatty liver disease [36], effectof oral GSH supplemen- tation on changes in erythrocyte GSH level [37, 38]
Oral supplements offer significant cost savings with home administration convenience
J Neurotrauma 2004
An alternative explanation, which could potentially explain both sets of experiments, is that exported GSH is broken down into constituent amino acids in the blood that are rapidly reimported into the liver cells
(PubMed) Nishiyama S, Mikeda T, Okada T, Nakamura K, Kotani T, Hishinuma A
When delivered through an IV, it enters your bloodstream directly, no digestion or breakdown, so your cells absorb it immediately