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The data released Tuesday increase significantly our confidence in that study, Chris Boshoff, Pfizers chief scientific officer, said on a call with analysts

Gut 1995, 37: 140-143

HO-1 plays a significant function in vascular tissues by safeguarding endothelial cells from various apoptotic stimuli, thereby regulating endothelial cell cycle control, proliferation, vascular endothelial growth factor (VEGF) secretion, and angiogenesis [94, 95]

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Custom ranges of amino acid mutations were defined for each position in the design chain to optimize the affinity and specificity of the peptides

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