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Toxicity of repeated oral intake of organic selenium, inorganic selenium, and selenium nanoparticles: a review

The systemic administration of nanoparticles loaded with doxorubicin, furthermore, inhibited tumor-growth of SCC7 head and neck cancer xenograft models by over 70% compared to non-treated control mice and by over 40% in comparison with conventional free doxorubicin-treated mice without severe side effects

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This includes upregulation of ATM by 80% in breast cancer cells and 120% in prostate cells