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Most published research has used injectable forms, which bypass the digestive system

Cadmium exposure has been associated with impaired spermatogenesis, DNA fragmentation, and reduced sperm motility, with studies showing a direct correlation between elevated cadmium levels in the blood or semen and poorer semen quality (58)

[DOI] [PMC free article] [PubMed] [Google Scholar] [98].Horowitz DM, Furie RA

This defined stoichiometry means each molecule delivers exactly one copper ion, allowing researchers to calculate precise copper concentrations in their experimental systems a critical consideration since copper is biologically active at nanomolar concentrations but cytotoxic at micromolar levels

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doi: 10.4103/2152-7806.174896