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This side effect appears to be driven by multiple factors, including Mounjaros impact on the brain, reduced peripheral blood flow, decreased thermogenesis from lower food intake, and reduced insulation from weight loss

Because of the social stigma associated with obesity, mental health issues, including sadness, anxiety, and poor self-esteem are common

However, as was the case with SSRIs and SNRIs, post-approval real-world data will be essential to confirm the safety profiles of the drugs and document potential adverse events or withdrawal syndrome that may arise with long-term use [148, 149]

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A recent study from Johns Hopkins School of Medicine shows that a molecule called NLY01, which can cross the blood-brain barrier, BBB, and enter the brain, is helpful in protecting nerve cells in mouse models of Parkinson's disease

Some of these precautions are mentioned in the following text