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Toxicity and antigenicity have not been detected in our studies with the peptides in animals (Eggink et al., 2018)

Fasting glucose and HbA1c: Baseline and at 8 weeks

49 Bulk and single-nucleus RNA-seq analyses of muscle biopsies across the lifespan identified reduced MuSC abundance with age and downregulation of ECM-related genes

3.3.2.1 Urolithin A Urolithin A, a natural gut metabolite of ellagic acid and ellagitannins, rich in nuts, is a safe mitophagy activator ( via promoting Nrf2 translocating into nucleus (Zhang et al., 2022c), but also ameliorates hyperuricemic nephropathy via enhancing PINK1-associated mitophagy in renal TECs (Zhang et al., 2022a)

F., Shah, R., Pratt, D

doi:10.1152/physrev.00034.2006