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Under normal conditions, it inhibits autophagy, an effect reversed by HDM2-mediated degradation of p53 during nutrient deprivation or stress
Targeted disruption of HLA genes via CRISPR-Cas9 generates iPSCs with enhanced immune compatibility
Who it's for: Patients wanting to understand genetic contributors to chronic illness, inflammation, methylation, detoxification capacity, or treatment response
References Carneiro BA, El-Deiry WS
Repairing DNA and preserving immune function protects your body from long-term consequences like skin cancer and aging too quickly
Genet Res Int 2014 , 698574 (2014)
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