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A Dionex UltiMate 3000 506 LC System (Thermo Scientific) and a Q Exactive Orbitrap mass spectrometer (Thermo Scientific) operated in negative mode was used for targeted measurement

Intraperitoneal insulin delivery to patients with type 1 diabetes results in higher serum IGF-I bioactivity than continuous subcutaneous insulin infusion

10.1080/15548627.2020.1752548 29 Di PietroM.ParborellF.IrustaG.PascualiN.BasD.BianchiM

Early findings suggest promising effects on body composition, including reductions in visceral fat accumulation, though further research is required to fully elucidate its long-term safety and efficacy