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This cavity accommodates the octanoyl group of ghrelin
@Amgen thinks so, releases @Nature phase 1 study of AMG 133 (maridebart cafraglutide) a combination of GIPR antagonist monoclonal anti- body and two GLP-1 agonist peptides Safe, tolerable with dose-dependent weight loss maintained to 150 days go.nature.com/3HUHBjB Will 2 incretin drugs be better than 1 to for weight loss & to prevent weight regain
Biology will defend against weight loss
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Youle RJ, Karbowski M
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