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Grey Literature Search dates : March 25-April 1, 2022 Keywords : Wegovy (semaglutide), weight management Limits : Publication years: none Updated : Search updated before the completion of stakeholder feedback period Relevant websites from the following sections of the CADTH grey literature checklist Grey Matters: A Practical Tool for Searching Health-Related Grey Literature were searched: Health Technology Assessment Agencies Health Economics Clinical Practice Guidelines Drug and Device Regulatory Approvals Advisories and Warnings Drug Class Reviews Clinical Trials Registries Databases (free) Internet Search Open Access Journals Appendix 2

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There is limited data on use in patients with decompensated cirrhosis or severe hepatic impairment (Child-Pugh class C), and consultation with hepatology specialists is advisable in these cases

Chakhtoura, M