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If this happens, the integrity of the compound is compromised, and for research purposes, it should ideally be discarded to avoid skewed results

A scoping review in Cureus (2025) added important context: dual-acting agonists like tirzepatide which targets both GLP-1 and GIP receptors produced greater reductions in weight and insulin sensitivity than GLP-1-only agents

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Sermorelin may still support fat loss by improving sleep quality (which supports metabolic regulation), enhancing GH-mediated lipolysis, preserving lean muscle mass, improving energy levels that support physical activity, and optimizing hormonal balance for better metabolic function