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A qualified provider will typically look at your serum B12 levels to see how your body is responding

The two are at different levels of evidence, which is something to be aware of in practical considerations

When To Take High-Dose Vitamin B12 Supplements Treating Vitamin B12 Deficiency People take high-dose vitamin B12 to treat a vitamin deficiency (levels below 200 to 250 pg/mL)

NASO B12 NASAL SPRAY is used as a maintenance therapy in adult patients with pernicious anaemia who are in remission status following intramuscular vitamin B12 therapy