The challenge with many interventions is that they lack selectivity, affecting multiple physiological systems simultaneously and creating side effects that limit their practical application or raise safety concerns
Safety concerns included uncharacterized immunogenicity (the risk that injected peptides trigger immune reactions), inadequate impurity and endotoxin testing in available raw material, the unresolved free base versus acetate salt form distinction, and, for BPC-157 specifically, an angiogenesis mechanism that raises theoretical cancer-risk concerns for certain patient populations
Many peptide protocols include on/off cycles rather than continuous use to minimize tolerance and risk
It could also increase GPX activity, thereby exerting antioxidative effects in rats [166]
More BAC water = lower concentration per unit drawn
PCR primers were purchased from Metabion