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This does not mean regulation is useless

doi: 10.1136/bjsports-2017-097608

doi: 10.3390/molecules26123486 384 El Adaouia TalebRDjebliNCheniniHSahinHKolayliS

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These should jointly assess SIRT1 activity, NRF2-related redox pathways, oxidative stress and cytokine panels, and SCFAs and other microbiota-derived metabolites alongside clinical outcomes, ideally within multi-omic frameworks of the dietmicrobiotametabolome axis