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Mechanism of PINK1 activation by autophosphorylation and insights into assembly on the TOM complex

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25 NADPH also acts as a cosubstrate for dihydropyrimidine dehydrogenase (DPYD), which catalyzes the reduction of uracil and thymine to 5,6-dihydrouracil and 5,6-dihydrothymine, respectively

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15 Based on the present results, we hypothesize that food-derived glutathione has beneficial effects on chronic diseases by activating the host antioxidant enzymatic systems and mitochondrial biogenesis through the hydrogen atomthiol compound exchange reaction on glutathione