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Celebioglu and Uyar, 2020)
The forces exerted by the fluid components in the tumor are called fluid stress. These forces include the microvascular and interstitial fluid pressures (MVP and IFP, respectively), as well as the shear stress exerted by blood and lymphatic flow on the vessel wall and by interstitial flow on cancer and stromal cells as well as extracellular matrix (Koumoutsakos et al., 2013)
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Subsequently, the undiluted samples were analyzed on an HPLC system (1200 series, Agilent Technologies Deutschland GmbH, Bblingen, Germany) with an organic acid resin column (300 mm 8 mm) and the corresponding pre-column (40 mm 8 mm) (Chromatographie-Service GmbH, Langerwehe, Germany) heated to 60C
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