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It is one of the very few animal peptides to contain a D-amino acid (D-alanine at position 2), an unusual feature that is generated post-translationally by enzymatic conversion of an L-alanine encoded in the gene [2]

The SURPASS-J-combo trial embraced diabetic adults with HbA 1c 7% to 11% and BMI 23 kg/m 2 , stable weight and uncontrolled with therapy of metformin, thiazolidinedione, sulfonylureas, meglitinide, alpha-glucosidase inhibitor or SGLT2-i (81)

BPC-157 is not on the WADA Prohibited List as of the latest WADA update, although classification is reviewed in each WADA cycle and is subject to change

In terms of side effects and tolerability, the advantage goes to CagriSema

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