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To investigate, they analyzed retrospective data from 16,827 Mass Eye and Ear patients

What the Clinical Evidence Says About GLP-1 and Male Reproduction Multiple clinical trials and observational studies have examined GLP-1 receptor agonists in men with obesity and type 2 diabetes without identifying direct reproductive toxicity or impaired sperm production

2019 Jan;33(1):10-21

Youve done the preliminary work

The American Association of Clinical Endocrinology (AACE) 2023 consensus statement on obesity pharmacotherapy recommends dose reduction or titration pause when GI side effects "interfere with daily activities or nutritional intake" 24

After four days, your provider may increase it to 300 mg once daily, which is the most commonly prescribed dose