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For instance, repeated cocaine in rodents enhanced histone H3 acetylation at the BDNF promoter in PFC, boosting BDNF transcription 175

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Understanding the pathogenetic roles of the various molecules in RA could facilitate discovery of potential therapeutic targets and approaches

Gocher AM, Azabdaftari G, Euscher LM, Dai S, Karacosta LG, Franke TF, et al

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This is due to the possibility that more glycine and serine may be needed to properly catabolize the extra methionine, unintentionally leading to a shortage in these amino acids