ADs such as SLE are suspected to have a microbial aetiology that may amplify the risk of disease development in genetically susceptible individuals, particularly those with a first-degree relative previously diagnosed with SLE (Navarra et al
You use the entire vial, nothing wasted, and then reconstitute a fresh vial for the next dose level
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Pernicious anaemia is a condition where vitamin B12 cannot be absorbed into your body
Gastrointestinal symptoms (more common with oral preparations): Mild nausea or upset stomach Diarrhoea (typically with very high doses) Other effects: Headache, particularly when treatment is first initiated Dizziness or light-headedness Skin reactions such as mild rash or itching Temporary reddish discolouration of urine (chromaturia) after hydroxocobalamin injections, which is harmless It is important to note that many symptoms attributed to B12 supplementation may actually represent the body's response to correcting a deficiency
However, some observational studies have linked very high supplemental intakes of B12 with potential health risks, including increased rates of certain cancers or fractures in specific populations
