Ketoconazole Size:50 g dilute or add reducing agent

dilute or add reducing agent before loading

Copy number: High Copy

How It Works: Tris buffers the extraction mix at ~pH 8

Promoter: TFEB

Prodrug conversion: In vivo (or in cellular systems)

Ketoconazole Size:50 g dilute or add reducing agentKetoconazole is a broad spectrum imidazole antifungal effective against a variety of fungal species including Candida species, Blastomyces species, and Histoplasma species. Ketoconazole functions by inhibiting ergosterol synthesis and increasing fungal cell membrane permeability. It is also a CYP3A4 inhibitor used to identify p glycoprotein CYP3A limited bioavailability and to study interleukin 1 chemotherapeutic effects. It has also been used to