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This graph diagrams utilization, unit cost, and cost as a percent of overall medical cost trend: note that by the middle of 2023, GLP-1 drug costs for Group health plan members comprised 13.6% of a major pharmacy benefit management (PBM) company, shown in the third bar

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The IRS-1 G972R Polymorphism and Type 2 Diabetes: A Paradigm for the Difficult Ascertainment of the Contribution to Disease Susceptibility of Low Frequency-Low Risk Variants. Nesti, Lorenzo, et al

It can be used as monotherapy or in combination with other diabetes medications, such as metformin or insulin

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