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Frontiers in pharmacology, 5, 151

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Synthesis of carnosine in humans Synthesis of carnosine from -alanine and histidine is catalyzed by ATP-dependent carnosine synthetase (a cytosolic enzyme) (Wu 2013), which is primarily present in skeletal muscle, heart, and certain brain regions (e.g., the olfactory bulb) (Drozak et al

A central component of APAP-induced hepatotoxicity is the activation of innate immune responses, particularly via inflammasome pathways

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