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Furthermore, in a BK5.IGF-1 mouse model of breast cancer, elevated levels of IGF-1 expression activated the COX-2/PGE2/EP3 signaling pathway, accompanied by increased VEGF expression and tumor angiogenesis (110)

PLoS ONE 6:e26575 Eda S, Sherman IW (2002) Cytoadherence of malaria-infected red blood cells involves exposure of phosphatidylserine

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Journal of Molecular Medicine (2017) Research demonstrating enhanced angiogenesis with BPC-157 in ischemic rat hind-limb muscle and vascular endothelial cells, via increased expression and internalization of VEGFR2 (but not VEGF-A).

During inflammatory bowel disease, colonic cells ramp up PepT1 expressioncreating disease-specific targeting in research models