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Educate patients that: Gastrointestinal side effects are common early on Symptoms are typically temporary and improve over time Side effects are often more noticeable during dose escalation Providers can adjust dosing if symptoms become difficult to manage 2

Notably, Vinukonda and colleagues [609] demonstrated that supervised classifiers trained on MRI data significantly outperformed traditional statistical methods in identifying early-stage AD

Growth hormone secretagogues (peptide therapy) support neuronal repair and cognitive clarity through improved GH levels

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Gaboxadol, a -subunit-selective, extrasynaptic GABAA receptor agonist that rescues FXS-related behaviors in Fmr1 KO mice, such as aggression, anxiety, hyperactivity, and stereotypies (153)

The unique renal sulfhydryl acid metabolic pathway, involving degradation of GSH by GGT, contributes to cisplatin nephrotoxicity (163)