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27,28 (2) Tuberous sclerosis complex 1/2 (TSC1/2) and proline-rich Akt substrate 40 (PRAS40) are inhibitors of mTORC1, thereby inducing protein synthesis and adipogenesis

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Weight loss itself can improve fertility outcomes in people with obesity, since excess body fat disrupts insulin sensitivity and hormone balance

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Similar uptake of exendin-4-FITC and lixisenatide-FITC was observed by confocal microscopy (Figure 4D)