The short version: tirzepatide tends to produce greater weight loss in clinical trials (up to 22.5% body weight versus 15% for semaglutide at maximum doses)
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But, these studies also found that decreasing oxidative stress post-exercise can negatively interfere with muscle growth and adaptation to exercise
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If you have some of those symptoms especially if you have a low red blood cell count you should talk to your doctor about further blood tests for vitamin B12
Studies of semaglutide show roughly 2540% of total weight lost comes from lean mass rather than fat