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Athletes and fitness enthusiasts increasingly use L-carnitine to boost endurance and improve post-exercise recovery, with reports indicating 45% of supplement users consumed sports nutrition in 2025, according to the Council for Responsible Nutrition

In previous clinical trials, since depression was not the primary prespecified outcome, most of them did not systematically track mood changes, which may lead to an underestimation of the real risk of adverse mental events during the clinical trial stage [28, 29]

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Peptic Ulcer Disease Peptic ulcer disease is the most common cause of melena (Fig

Figure 6 Statements Data availability statement The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation

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