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Synopsis Tobacco Effects: How It Harms the Body and Fuels Addiction Tobacco contains nicotine, a powerful, highly addictive substance

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Pharmacologic agents that have not received FDA approval for use in smoking cessation but have demonstrated efficacy are clonidine and nortriptyline

[5] Growing public concern about the health risks associated with smoking prompted Brown and Williamson to release filtered varieties of Kool: an 85-millimeter "king-sized" version in the 1960s, followed by a 100-millimeter or "long" version in the 1970s.Newport

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