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For alcohol, marijuana, cocaine, heroin, and methamphetamine in Table 1 , respondents were classified as having an SUD in the past year if they met 2 or more of the 11 criteria in the 12month period before the interview

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The common clinical presentation was anorexia, brown pigmentation, peripheral neuritis (muscular weakness, pain and paresthesias in extremities), hepatic lesions, localized edema, and fatty degeneration of the heart

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