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If nausea persists beyond 5 days post-injection or intensifies over consecutive weeks, this signals a need to pause dose escalation for an additional 24 weeks rather than pushing forward

Empirical evidence indicates that these organizations often reach similar conclusions about the relative value of therapies once price is accounted for: a drug deemed to provide only modest benefit at high cost will be ranked low by both ( [12] ) ( [13] )

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Discussing alternative therapies or having regular nutrient IV therapy and/or vitamin B12 injections can help