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The oxidation of the fusion-constructs was followed by mixing 2 M reduced protein in syringe 1 with variable concentrations of GSSG in syringe 2

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62,100 Additionally, mitochondrial iron uptake, MPTP opening, and liver injury were significantly reduced in MCFU gene knockout mice exposed to APAP, 101 and selective chelation of iron in lysosomes with starch-desferal and the general iron chelator DFO also effectively prevented APAP-induced liver injury