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[DOI] [PMC free article] [PubMed] [Google Scholar] 56.Sagit M., Polat H., Gurgen S.G., Berk E., Guler S., Yasar M

Consistent topical use can produce meaningful improvements in surface texture and hydration, particularly when applied post-microneedling when the barrier has been temporarily disrupted

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Treatment also produces beneficial changes in plasma lipid profiles, decreasing total cholesterol levels by approximately 30%, bringing these values to levels comparable with normal-weight controls

Microneedling is most effective for mild to moderate sagging neck skin and texture concerns